John Cena vs. Brock Lesnar To Open WWE Wrestlepalooza

As noted before, Joe Tessitore had announced earlier this month during an interview with ESPN’s SportsCenter that the John Cena vs. Brock Lesnar match would be main eventing WWE’s Wrestlepalooza event on September 20th at the Gainbridge Fieldhouse in Indianapolis, Indiana.

Thursday’s episode of The Pat McAfee Show featured co-host Pat McAfee revealing that Cena vs. Lesnar will now be opening Wrestlepalooza instead. A graphic was then shown on the screen featuring the match graphic containing the text of “John Cena vs. Brock Lesnar Kicks Off The ESPN-WWE Era.”

BREAKING NEWS: John Cena and Brock Lesnar will be KICKING OFF Wrestlepalooza #PMSLive pic.twitter.com/H2F5hoZHuZ

— Pat McAfee (@PatMcAfeeShow) September 18, 2025

Current card for WWE Wrestlepalooza:

• Undisputed WWE Championship – Drew McIntyre vs. Cody Rhodes (c)
• Vacant WWE Women’s World Championship – Stephanie Vaquer vs. IYO SKY
• The Usos (Jimmy & Jey Uso) vs. “Big” Bronson Reed & Bron Breakker
• Mixed Tag Team match – Becky Lynch & Seth Rollins vs. AJ Lee & CM Punk
• John Cena vs. Brock Lesnar